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  • 焼酎学コース
  • 国立大学法人鹿児島大学
  • 鹿児島大学大学院連合農学研究科

    • Ⅰ．受賞

    ２００８年第９回酵素応用シンポジウム研究奨励賞受賞
    「耐熱性セルラーゼを生産する耐熱性酵母の構築」

    Ⅱ．科学研究費

    https://kaken.nii.ac.jp/ja/search/?qm=20212045

    Ⅲ．学術論文（査読有）

    • Effect of pepA deletion and overexpression in Aspergillus luchuensis on sweet potato shochu brewing. Sho Setoguchi, Osamu Mizutani, Osamu Yamada, Taiki Futagami, Kenichi Iwai, Yoshikazu Takase, and Hisanori Tamaki. J. Biosci. Bioeng.(2019) in press
    • Effect of maturation time on koji-like smell and volatile compounds of barley miso (Japanese soybean paste) during fermentation. Toshihiko Kojo, Mikihiko Kawai, Yohei Shiraishi, Shugo Kurazono, Chihiro Kadooka, Kayu Okutsu, Yumiko Yoshizaki, Makoto Ikenaga, Taiki Futagami, Kazunori Takamine, and Hisanori Tamaki. (2019) Food Science and Technology Research, 25(2),
    • Mitochondrial citrate transporters CtpA and YhmA are involved in cytosolic acetyl-CoA biosynthesis in the white koji fungus, Aspergillus luchuensis mut. kawachii Chihiro Kadooka, Kosuke Izumitsu, Masahira Onoue, Kayu Okutsu, Yumiko Yoshizaki, Kazunori Takamine, Masatoshi Goto, Hisanori Tamaki, Taiki Futagami. (2019) Appl. Environ. Microbiol., 85(8) pil:e03136-18. doi: 10.1128/AEM.03136-18.
    • Pex16 is involved in peroxisome and Woronin body formation in the white koji fungus, Aspergillus luchuensis mut. kawachii. Daichi Kimoto, Chihiro Kadooka, Pakornkiat Saenrungrot, Kayu Okutsu, Yumiko Yoshizaki, Kazunori Takamine, Masatoshi Goto, Hisanori Tamaki, Taiki Futagami. (2019) J. Biosci. Bioeng., 127(1): 85-92. doi: 10.1016/j.jbiosc.2018.07.003.
    • 芋焼酎の発酵および酒質に及ぼす二次醪pHの影響　髙峯和則、小島舞、奥津果優、二神泰基、玉置尚徳、吉﨑由美子(2018) 日本醸造協会誌、113(6), 375-382
    • Characterization of amylolytic enzyme overproducing mutant of Aspergillus luchuensis obtained by ion beam mutagenesis. Toshihiro Kojo, Chihiro Kadooka, Marisa Komohara, Shiori Onitsuka, Miya Tanimura, Yukiko Muroi, Shugo Kurazono, Yohei Shiraishi, Ken Oda, Kazuhiro Iwashita, Masahira Onoue, Kayu Okutsu, Yumiko Yoshizaki, Kazunori Takamine, Taiki Futagami, Kazuki Mori, and Hisanori Tamaki. (2018) J. Gen. Appl. Microbiol.63(6):339-346 doi: 10.2323/jgam.2017.02.004.
    • Genome sequence of Saccharomyces cerevisiae strain Kagoshima no. 2, used for brewing the Japanese distilled spirit shochu. Kazuki Mori, Chihiro Kadooka, Chika Masuda, Ai Muto, Kayu Okutsu, Yumiko Yoshizaki, Kazunori Takamine, Taiki Futagami, and Hisanori Tamaki. Genome Announc 5(41) e01126-17
    • プロテアーゼまたは細胞壁分解系酵素剤添加による紅麹焼酎製造法の改良,吉﨑由美子、奥津果優、二神泰基、玉置尚徳、鮫島吉廣、髙峯和則 (2017)日本醸造協会誌、113(4), 265-272
    • Multi-gene phylogenetic analysis reveals that shochu-fermenting Saccharomyces cerevisiae strains form a distinct sub-clade of the Japanese sake cluster. Taiki Futagami, Chihiro Kadooka, Yoshinori Ando, Kayu Okutsu, Yumiko Yoshizaki, Shinji Setoguchi, Kazunori Takamine, Mikihiko Kawai, Hisanori Tamaki. Yeast, 34(10): 407-415 doi: 10.1002/yea.3243
    • Key volatile compounds in red koji-shochu, a Monascus-fermented product, and their formation steps during fermentation. Yen Yen Sally Rahayu, Yumiko Yoshizaki, Keiko Yamaguchi, Kayu Okutsu, Taiki Futagami, Hisanori Tamaki, Yoshihiro Sameshima, Kazunori Takamine. (2017) Food Chem., 224, 398-406
    • 奥津果優，門岡千尋，小城章裕，吉崎由美子，二神泰基，玉置尚徳，髙峯和則. 中国及び韓国の市場品「神麹」における菌叢と含有成分の実態調査.(2017) 生薬学雑誌、第71巻第1号　41-48
    • Marker recycling system using the sC gene in the white koji mold, Aspergillus
    • luchuensis mut. kawachii. Kadooka, C., Onitsuka, S., Uzawa, M., Tashiro, S.,
    • Kajiwara, Y., Takashita, H., Okutsu, K., Yoshizaki, Y., Takamine, K., Goto, M., Tamaki, H., Futagami T. (2016) J. Gen. Appl. Microbiol. 62, 160-163,
    • Characteristic odour compounds in shochu derived from rice koji. Yohei Shiraishi,Yumiko Yoshizaki, Toshifumi Ono, Hiroaki Yamato, Kayu Okutsu, Hisanori Tamaki, Taiki Futagami, Sameshima Yoshihiro, and Kazunori Takamine (2016) J. Inst. Brew., 122, 381-387
    • Effects of the cultivation period of sweet potato on the sensory quality of imo-shochu, a Japanese traditional spirit. Okutsu, Kayu; Yoshizaki, Yumiko; Kojima, Mai; Yoshitake, Kazuya; Tamaki, Hisanori; Kazunori, Takamine (2016) J. Inst. Brew., 122, 168-174
    • サツマイモの加熱方法が芋焼酎香気に与える影響、吉﨑由美子，松山晃佑，大庭暁紘，園田舟，奥津果優，玉置尚徳，髙峯和則 (2015)日本醸造協会誌 110(5), 349-356
    • 韓国伝統的麹「ヌルク」を用いた焼酎製造の可能性、吉崎由美子，金顯民，奥津果優，池永誠，玉置尚徳，髙峯和則　(2015) 日本醸造協会誌，110(3)，170-178
    • サツマイモに含まれるモノテルペン配糖体の分布．髙峯和則, 吉﨑由美子，山本優，吉竹一哉，橋本文雄，玉置尚徳，鮫島吉廣(2012)日本醸造学会誌　 107, 782-787
    • Kluyveromyces marxianus-based Platform for Direct Ethanol Fermentation and Recovery from Cellulosic Materials Under Air-Ventilated Condition. Matsuzaki, C., Nakagawa, A., Koyanagi, T., Tanaka, K., Minami, H., Tamaki, H., Katayama, T., Yamamoto, K., and Kumagai, H. (2012) J. Biosci. Bioeng., 113 (5), 604-607
    • Development of a heat-processing method for koji to enhance its antioxidant activity. Okutsu, K., Yoshizaki, Y., Takamine, K., Tamaki, H., Ito, K., and Sameshima, Y. (2012) J. Biosci. Bioeng., 113 (3), 349-354
    • The formation of beta-damascenone in sweet potato shochu, Yoshizaki, Y., Takamine, K., Shimada, S., Uchihori, K., Okutsu, K., Tamaki, H., Ito, K., and Sameshima Y. (2011) J. Inst. Brew. 117, 217-223
    • 酒類としてのミキの製造.　久留ひろみ, 吉崎由美子, 玉置尚徳, 和田浩二, 伊藤清(2011)日本醸造学会誌　106(3)、157-163
    • 芋焼酎に検出されたローズオキサイドの生成機構. 高峯和則，吉崎由美子，島田翔吾，高屋総一郎，玉置尚徳，伊藤清，鮫島吉廣(2011)日本醸造学会誌　106(1)、50-57
    • 奄美大島の伝統飲料「ミキ」中の乳酸菌.　久留ひろみ、玉置尚徳、和田浩二、伊藤清 (2010) 日本醸造学会誌、105(11)、741-748
    • Characterization of glucoamylase and α-amylase from Monascus anka: Enhanced
    • production of α-amylase in red koji. Yoshizaki, Y., Susuki, T., Takamine, K., Tamaki, H., Ito, K., and Sameshima Y. (2010) J. Biosci. Bioeng., 110(6), 670-674.
    • Role of a PA14 domain in determining substrate specificity of a glycoside hydrolase family 3 β-glucosidase from Kluyveromyces marxianus. Yoshida, E., Hidaka, M., Fushinobu, S., Koyanagi, T., Minami, H., Tamaki, H., Kitaoka, M., Katayama, T., and Kumagai, H. (2010) Biochem. J., 431(1), 39-49
    • 土壌からの焼酎酵母の分離と分離酵母の実用化. 高峯和則、大山修一、吉崎由美子、玉置尚徳、鮫島吉廣 (2010) 日本醸造学会誌、105(8)：546-555
    • Analysis of Volatile Compounds in Shochu Koji, Sake Koji, and Steamed Rice
    • by Gas Chromatography-Mass Spectrometry. Yoshizaki, Y., Yamato, H., Takamine, K., Tamaki, H., Ito K., and Sameshima Y. (2010) J. Inst. Brew. 116(1), 49–55.
    • 奄美大島の伝統飲料「ミキ」の分析．久留ひろみ、吉崎(尾花)由美子、玉置尚徳、和田浩二、伊藤清 (2010) 日本醸造学会誌、105(3)、167-174
    • Purification, crystallization and preliminary X-ray analysis of b-glucosidase from
    • Kluyveromyces marxianus NBRC1777. Yoshida, E., Hidaka, M., Fushinobu, S., Koyanagi, T., Minami, H., Tamaki, H., Kitaoka, M., Katayama, T., Kumagai, H. (2009) Acta Crystallogr Sect F Struct Biol Cryst Commun. 65, 1190-1192.
    • Loss of heterozygosity is induced in Candida albicans by ultraviolet irradiation. Takagi, Y., Akada, R., Kumagai, H., Yamamoto, K., and Tamaki, H. (2008) Appl. Microbiol. Biotechnol., 77, 1073-1082
    • LPT1 encodes a membrane-bound O-acyltransferase involved in the acylation of lysophospholipids in the yeast Saccharomyces cerevisiae. Tamaki, H., Shimada, A., Ito, Y., Ohya, M., Takase, J., Miyashita, M., Miyagawa, H., Nozaki, H., Nakayama, R., and Kumagai, H. (2007) J. Biol. Chem., 282, 34288-34298.
    • Glucose-Stimulated cAMP-PKA Pathway in Yeast Saccharomyces cerevisiae. Tamaki, H. (2007) J. Biotech. Bioeng., 104(4), 245-250.
    • Construction of thermotolerant yeast expressing thermostable cellulase genes. Hong, J., Wang Y., Kumagai, H., and Tamaki, H. (2007) J. Biotechnology, 130, 114-123.
    • Cloning and functional expression of thermo-stable b-glucosidase gene from Thermoascus aurantiacus. Hong, J., Tamaki, H., and Kumagai, H. (2007) Appl. Microbiol. Biotechnol., 73, 1331-1339.
    • Unusual hydrophobic linker region of b-glucosidase (BGLII) from Thermoascus aurantiacus are required for hyper activation by organic solvents. Hong, J., Tamaki, H., and Kumagai, H. (2006) Appl. Microbiol. Biotechnol., 73 (1), 80-88.
    • Glucose-dependent cell size is regulated by a G protein-coupled receptor system in yeast Saccharomyces cerevisiae. Tamaki, H., Yun, C.-W., Mizutani, T., Tsuzuki, T.  Takagi, Y., Shinozaki, M., Kodama, Y., Shirahige, K., and Kumagai, H. (2005) Genes Cells, 10 (3), 193-206.
    • Gpr1, a Putative G-Protein-Coupled Receptor, Regulates Morphogenesis and Hypha Formation in the Pathogenic Fungus Candida albicans. Miwa, T., Takagi, Y., Shinozaki, M., Yun, C.-W., Schell, W. A., Perfect, J. R., Kumagai, H., and Tamaki, H.(2004) Eukaryot. Cell, 3 (4), 919-931.
    • Characterization of heterotrimeric G protein complexes in rice plasma membrane.Kato, T., Mizutani, T., Tamaki, H., Kumagai, H., Kamiya, T., Hirobe, A., Fujisawa, Y., Kato, H., and Iwasaki, Y. (2004) Plant J., 38 (2), 320-331.
    • Gene Organization and Molecular Modeling of Copper Amine Oxidase from Aspergillus niger: Re-Evaluation of the Cofactor Structure. Frébort,, I., ebela, M, Hirota, S., Yamada, M., Tamaki, H., Kumagai, H., Adachi, O., and Pe, P. (2003) Biol. Chem., 384, 1451-1461.
    • Cloning of a gene encoding thermostable cellobiohydrolase from Thermoascus aurantiacus and its expression in yeast. Hong, J., Tamaki, H., Yamamoto, K., and Kumagai, H. (2003) Appl. Microbiol. Biotechnol. 63 (1), 42-50.
    • Cloning of a gene encoding thermo-stable endo-b-1,4-glucanase from Thermoascusaurantiacus and its expression in yeast. Hong, J., Tamaki, H., Yamamoto, K., and Kumagai, H. (2003) Biotechnology Lett. 25, 657-661
    • Cloning of a gene encoding a highly stable endo-b-1,4-glucanase from Aspergillus niger and its expression in yeast. Hong, J., Tamaki, H., Akiba, S., Yamamoto, K., and Kumagai, H. (2001) J. Bioscience and Bioeng., 92, 434-441.
    • GPR1 regulates filamentous growth through FLO11 in yeast Saccharomyces cerevisiae. Tamaki, H., Miwa, T., Shinozaki, M., Saito M., Yun, C.-W., Yamamoto, K., and Kumagai, H. (2000) Biochem. Biophys. Res. Commun., 267, 164-168.
    • Molecular Cloning of cDNA Encoding a-N-Acetylgalactosaminidase from Acremonium sp. and Its Expression. Ashida, H., Tamaki, H., Yamamoto, K., and Kumagai, H. Arch. Biochem. Biophys. 384(2) 305-310. (2000)　
    • Expression of two glutathione S-transferase genes in the yeast Issatchenkia orientalis is induced by o-dinitrobenzene during cell growth arrest. Tamaki, H., Yamamoto, K., and Kumagai, H. (1999) J. Bacteriology, 181, 2958-2962.
    • Gpr1p, a putative G-protein coupled receptor, regulates glucose dependent cellular cAMP level in yeast Saccharomyces cerevisiae. Yun, C.-W., Tamaki, H., Nakayama, R., Yamamoto, K. and Kumagai, H. (1998) Biochem. Biophys. Res. Commun., 252, 29-33
    • G-Protein Coupled Receptor from Yeast Saccharomyces cerevisiae. Yun, C.-W., Tamaki, H., Nakayama, R., Yamamoto, K., and Kumagai, H. (1997) Biochem. Biophys. Res. Commun., 240, 287-292
    • Vanilin formation by microbial amine oxidases from vanillylamine. Yoshida, A., Takenaka, Y., Tamaki, H., Frébort, I, Adachi, O., Kumagai, H. (1997) J. Ferment. Bioeng., 84, 603-605
    • Cloning and nucleotide sequence of the b-D-glucosidase gene from Bifidobacterium brebe clb, and expression of b-D-glucosidase activity in Escherichia coli. Nunoura, N., Ohdan, K., Tanaka, K., Tamaki, H., Yano, T., Inui, M., Yukawa, H., Yamamoto, K, Kumagai, H. (1996) Biosci. Biotech. Biochem. 60(12), 2011-2018
    • Two distinct quinoprotein amine oxidases are induced by n-butylamine in mycelia of Aspergillus niger AKU 3302. Frebort, I., Tamaki, H., Ishida, H., Pec, P., Luhova L., Tsuno, H., Halata, M., Asano, Y., Kato, Y., Matsushita, K., Toyama, H., Kumagai, H., and Adachi, O. (1996) Eur. J. Biochem., 237, 255-265
    • Nucleotide sequence of the yeast glutathione S-transferase cDNA; Tamaki, H., Kumagai, H., Tochikura, T.(1991) Biochim. Biophys. Acta, 1089 (276-279)
    • Detoxification metabolism of o-dinitrobenzene by yeast Issatchenkia orientalis; Tamaki, H., Kumagai, H., Shimada, Y., Kashima, T., Obata, H., Kim, C.-S., Ueno, T., Tochikura, T. (1991) Agric. Biol. Chem., 55 (951-956)
    • Glutathione S-transferase in yeast : Induction of mRNA, cDNA cloning and expression in Escherichia coli;  Tamaki, H., Kumagai, H., Tochikura, T. (1990) Biochem. Biophys. Res. Commun., 172 (669-675)
    • Purification and properties of glutathione transferase from Issatchenkia orientalis;  Tamaki, H., Kumagai, H., Tochikura, T. (1989) J. Bacteriol., 171 (1173-1177)
    • Distribution, formation and stabilization of yeast glutathione S-transferase; Kumagai, H., Tamaki, H., Koshino, Y., Suzuki, H., Tochikura, T. (1988) Agric. Biol. Chem. 52 (1377-1382)
    • Ammonia assimilation by glutamine synthetase/glutamate synthase system in Brevibacterium flavum; Sung, H.-C., Takahashi, M., Tamaki, H., Tachiki, T., Kumagai, H., Tochikura, T. (1985) J. Ferment. Technol., 63  (5-10)

    Ⅳ．著書

    • 片山高嶺、江口陽子、竹川薫、玉置尚徳、５章 微生物の遺伝子発現制御とシグナル伝達、遺伝子･細胞から見た応用微生物学、阪井康能、竹川薫、橋本渉、片山高嶺 編著、朝倉書店p65-81、2020年出版
    • 玉置尚徳、細胞膜リン脂質リモデリングへのアプローチ　中心的役割を担う新規リゾリン脂質アシル転移酵素を酵母で同定、化学と生物、47(1) 8-10, 2009
    • 内海龍太郎、片山高嶺、玉置尚徳、５章　細胞の調節とシグナル伝達、遺伝子から見た応用微生物学、熊谷英彦・加藤暢夫・村田幸作・阪井康能 編著、朝倉書店、p78-95、2008年出版
    • 玉置尚徳、アミノ酸合成の一般制御、酵母のすべて　系統,細胞から分子まで、大隅良典・下田親 編著、シュプリンガー・ジャパン（株）、p169-174、 2007年出版
    • Tamaki, H., and Kumagai, H. Glucose Sensing and Signal Transduction in Yeast. Proceedings of International Conference on Tropical Bio-resources and green chemistry strategy. pp315-319, 2002
    • 玉置尚徳、出芽酵母の栄養源認識と細胞形態変化、バイオサイエンスとインダストリー 59(7), 9-10, 2001
    • 玉置尚徳、出芽酵母における栄養源認識と偽菌糸形成,  生物工学会誌, 78, 139, 2000
    • 熊谷英彦、玉置尚徳、酵母Issatchenkia orientalis では、２種のグルタチオンS-トランスフェラーゼが、o-ジニトロベンゼンによる細胞増殖抑制中に誘導生成する,ビタミン, 74, 13-14, 2000
    • 玉置尚徳、出芽酵母において見つかったグルコース受容体, バイオサイエンスとインダストリー, 57(3), 179-180, 1999
    • 玉置尚徳、出芽酵母おける栄養源のシグナル伝達と２つのGタンパク質, 化学と生物, 36(9),589-590, 1998
    • 玉置尚徳、RNA結合アテニュエーションタンパク質に見られる新規なドーナツ構造、化学と生物、34(2), 106, 1996
    • Nakayama, R., Yun, C.-W., Tamaki, H., Saito, K., and Kumagai, H.  Physiological action of PAF in yeast Saccharomyces cerevisiae. in Platelet-activating factor and related lipid mediators 2. Adv. Exp. Med. Bio. pp45-50, Nigam et al., edited Plenum Press, New York 1996
    • 玉置尚徳、新規な酵素補欠分子TOPAキノンの生合成機構、生物工学会誌、73(4), 313, 1995
    • 玉置尚徳、癌細胞の放射線耐性、薬剤耐性とグルタチオン、ビタミン、68, 46-47, 1994
    • Purification and some properties of glutaminase from Schizosaccharomyces pombe; Arboleda, M., Tamaki, H., Yamamoto, K., Kumagai, H.(1994) Annual Reports of International Center of Cooperative Research in Biotechnology, Japan, 193-207
    • Glutathione S-transferase of a yeast Issatchenkia orientalis; Kumagai, H., Tamaki, H., Tochikura, T. (1992) in Frontiers and new horizons in amino acid research, pp587-588, K. Takai, ed., Elsevier, Amsterdam.

    Ⅴ．特許

    • 酵母の接合方法　特願2018-167542 (2018.9.7)
    • 真菌におけるタンパク質の選択的分泌技術　特願2016-2522330 (2016.12.27)
    • 血小板活性化因子の合成機能を有する遺伝子　特開2008-193913 (2008.8.28)
    • アミン酸化酵素をコードする遺伝子　特開平8-70872 (1996.3.19)