研究業績

これまでの主な業績(抜粋)

2018

[原著論文]

  • Ibrahim HR, Isono H, Miyata T. Potential antioxidant bioactive peptides from camel milk proteins. (2018) Anim. Nutr., 4:273-280

2017

[原著論文]

  • Hisham R. Ibrahim, Kosuke Hamasaki, Takeshi Miyata. Novel peptide motifs from lysozyme suppress pro-inflammatory cytokines in macrophages by antagonizing toll-like receptor and LPS-scavenging action. (2017) European Journal of Pharmaceutical Sciences 107:240-248
  • Ibrahim HR, Ahmed AS, Miyata T. Novel angiotensin-converting enzyme inhibitory peptides from caseins and whey proteins of goat milk. (2017) J. Adv. Res. 8:63-71
  • Kusakisako K, Miyata T, Tsujio M, Galay RL, Talactac MR, Hernandez EP, Fujisaki K, Tanaka T. Evaluation of vaccine potential of 2-Cys peroxiredoxin from the hard tick Haemaphysalis longicornis. (2017) Experimental and Applied Acarology 74(1):73-84

2016

[原著論文]

  • Kinoshita K, Shimogiri T, Ibrahim HR, Tsudzuki M, Maeda Y, Matsuda Y Identification of TENP as the Gene Encoding Chicken Egg White Ovoglobulin G2 and Demonstration of Its High Genetic Variability in Chickens. (2015) Pros One. 11:e0159571
  • Harakuni T, Andoh K, Sakamoto R, Tamaki Y, Miyata T, Uefuji H, Yamazaki K, Arakawa T. Fiber knob domain lacking the shaft sequence but fused to a coiled coil is a candidate subunit vaccine against egg-drop syndrome. (2016) Vaccine 34(27):3184-90.

2015

[原著論文]

  • Ahmed AS, El-Bassiony T, Elmalt LM, Ibrahim HR. Identification of potent antioxidant bioactive peptides from goat milk proteins. (2015) Food Res. Int. 74:80-88
  • Maeda H, Kurisu K, Miyata T, Kusakisako K, Galay RL, Rio TM, Mochizuki M, Fujisaki K, Tanaka T. Identification of the Babesia-responsive leucine-rich repeat domain-containing protein from the hard tick Haemaphysalis longicornis. (2015) Parasitol. Res.,114(5) 1793-802

2014

[原著論文]

  • Ibrahim HR, Tatsumoto S, Hajime O, Immerseel FV, Raspoet R, Miyata T. A novel antibiotic-delivery system by using ovotransferrin as targeting molecule. (2014) Eur. J. Pharm. Sci, 12;66C:59-69.
  • Arakawa T, Tsuboi T, Sattabongkot J, Sakao K, Torii M, Miyata T. Tricomponent complex loaded with a mosquito-stage antigen of malaria parasite induces potent transmission-blocking immunity. (2014) Clinical Vaccine and Immunology 21:561-9

2013

[原著論文]

  • Ibrahim H.R.; Hozono A.; Fukami M.; Shaban M.A.; Miyata T.” Expression of ovotransferrin enhances tolerance of yeast cells toward oxidative stress" J. Agri. Food Chem., 2013, 61 (26), pp 6358–6365
  • Miyata T, Tafuku S, Harakuni T, Tadano M, Yoshimoto N, Iijima M, Matsuo H, Matsuzaki G, Kuroda S, Arakawa T. A bio-nanocapsule containing envelope (E) protein domain III of Japanese encephalitis virus (JEV) protects mice against lethal JEV infection. (2013) Microbiology and Immunology 57:470-7.
  • Okuno T, Kashige N, Satho T, Irie K, Hiramatsu Y, Sharmin T, Fukumitsu Y, Uyeda S, Yamada S, Harakuni T, Miyata T, Arakawa T, Imoto M, Toda A, Nakashima Y, Miake F. Expression and secretion of cholera toxin B subunit in lactobacilli. (2013) Biol. Pharm. Bull. 36:952-8.

[学会発表]

2012

[原著論文]

  • Myint, S.L., Kinoshita, K., Shimogiri, T., Ibrahim, H.R., Tsusaki, T., Tanoue, T., Kawabe, K., Maeda, Y. and Okamoto, S. "Effect of polymorphism in egg white lysozyme on muramidase and antibacterial activities as well as hatchability in the Japanese quail (Coturnix japonica)" J. Anim. Sci. (JAS), 2012, 90 (6), 1747-1755.
  • Ibrahim, H.R., "Anti-infective drugs: why should we pay attention?" Outlook on Developing Drugs. Open Access (2012), 1-2.

2011

[原著論文]

  • Ibrahim, H.R., Imazato, K. and Ono, H. "Human lysozyme possesses novel antimicrobial peptides within its N-terminal domain that target bacterial respiration" J. Agri. Food Chem. 2011, 59 (18), 10336–10345.
  • Hoq, M.I. and Ibrahim, H.R.*,“Potent antimicrobial action of triclosan- lysozyme complex against skin pathogens mediated through drug-targeted delivery mechanism" Eur. J. Pharm. Sci., 2011, 42, 130-137.

2010

[原著論文]

  • Ibrahim, H.R., "Novel drug-targeting strategy from beneath the shell of egg". Expert Opin. Drug Deliv. 2010, 7, 1145-1158. 
     

2009

[原著論文]

  • Ibrahim, H.R. and Kiyono, T. “Novel anticancer activity of the auto-cleaved ovotransferrin against human colon and breast cancer cells”J. Agric. Food Chem. 2009, 57, 11383–11390.  [DOI:10.1021/jf902638e] 
  • Md. Imranul Hoq; Aoki, T.; Hisham R. Ibrahim, “Triclosan-Lysozyme Complex: A promising anti-microbial macromolecule stable against photooxidative damage" Food Res. Intl.  2009, 42, 298–306.

 

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食品機能化学講座 食品化学研究室

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